Cytotoxic cycloartane-type triterpenes from Combretum quadrangulare

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DOIResolve DOI: http://doi.org/10.1016/S0960-894X(98)00644-1
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TypeArticle
Journal titleBioorganic and Medicinal Chemistry Letters
ISSN0960-894X
Volume8
Issue24
Pages35193524; # of pages: 6
AbstractSeven novel cycloartane-type triterpenes were isolated from Combretum quadrangulare, and their structures were elucidated on the basis of spectral analysis. All these compounds were tested for their cytotoxicity against murine colon 26-L5 carcinoma cells. Methyl quadrangularate B (2) and methyl quadrangularate D (4) exhibited potent cytotoxicity having ED50 values 9.54 and 5.42 μM, respectively.
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LanguageEnglish
Peer reviewedYes
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NPARC number21275307
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Record identifierd58a91f7-f25b-4256-a13a-df77e81a3bc7
Record created2015-06-04
Record modified2016-05-09
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