Detection of the Pseudomonas Quinolone Signal (PQS) by cyclic voltammetry and amperometry using a boron doped diamond electrode

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DOIResolve DOI: http://doi.org/10.1039/c1cc13997e
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TypeArticle
Journal titleChemical Communications
ISSN1359-7345
Volume47
Issue37
Pages1034710349; # of pages: 3
Subjectboron; diamond; pseudomonas quinolone signal; quinolone derivative; unclassified drug; amperometry; article; bacterial strain; bacterium culture; cyclic potentiometry; electrochemistry; electrode; nonhuman; protein analysis; Pseudomonas aeruginosa; quorum sensing; Boron; Diamond; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Pseudomonas; Quinolones; Quorum Sensing
Abstract2-Heptyl-3-hydroxy-4-quinolone, known as the Pseudomonas Quinolone Signal, is a key regulator of bacterial cooperative behaviour known as quorum sensing. A simple electrochemical strategy was employed for its sensitive detection using a bare boron-doped diamond electrode by cyclic voltammetry and amperometry. PQS (and potentially other quinolones) was then detected in cultures of P. aeruginosa pqsL - mutant strains. © 2011 The Royal Society of Chemistry.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Biotechnology Research Institute (BRI-IRB)
Peer reviewedYes
NPARC number21271240
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Record identifierd649cd16-5da1-4a42-8395-ef9dd00e1468
Record created2014-03-24
Record modified2016-05-09
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