Carbon dioxide clathrates : an IR spectroscopic marker for arthritis?

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DOIResolve DOI: http://doi.org/10.1366/0003702934067586
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TypeArticle
Journal titleApplied Spectroscopy
ISSN0003-7028
1943-3530
Volume47
Issue9
Pages15191521; # of pages: 3
SubjectInfrared; Interferometry; mid_IR; Molecular structure; Spectroscopic techniques; Carbon dioxide clathrates; Synovial fluid
AbstractThe IR spectra of dry films of synovial fluid from normal and arthritic joints are presented. The spectra suggest the existence of CO₂ clathrates in these fluids which are of remarkable stability in comparison to well-known CO₂ clathrate hydrates. To our knowledge, this is the first demonstration of the formation of CO₂ clathrates in biological media. The proportion of CO₂ clathrates found in synovial fluid appears to vary with the state of health of joints and thus may be of use in the clinical diagnosis of arthritis.
Publication date
PublisherSociety for Applied Spectroscopy
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Biodiagnostics
Peer reviewedYes
NRC number17
NPARC number9742526
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Record identifierd6c46601-47d1-45db-81e7-d2aa4f386777
Record created2009-07-17
Record modified2016-12-09
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