NIR spectroscopic imaging to map hemoglobin + myoglobin oxygenation, their concentration and optical pathlength across a beating pig heart during surgery

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DOIResolve DOI: http://doi.org/10.1002/jbio.201100031
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TypeArticle
Journal titleJournal of Biophotonics
Volume5
Issue2
Pages128139; # of pages: 12
SubjectNIR spectroscopic imaging; pig heart in vivo; hemoglobin +; myoglobin oxygenation and concentration; optical pathlength
AbstractThe purpose of this paper is to demonstrate that near-infrared (NIR) spectroscopic imaging can provide spatial distribution (maps) of the absolute concentration of hemoglobin + myoglobin, oxygen saturation parameter and optical pathlength, reporting on the biochemico-physiological status of a beating heart in vivo. The method is based on processing the NIR spectroscopic images employing a first-derivative approach. Blood-pressure-controlled gating compensated the effect of heart motion on the imaging. All the maps are available simultaneously and noninvasively at a spatial resolution in the submillimeter range and can be obtained in a couple of minutes. The equipment has no mechanical contact with the tissue, thereby leaving the heart unaffected during the measurement
Publication date
LanguageEnglish
AffiliationNRC Institute for Biodiagnostics; National Research Council Canada
Peer reviewedYes
NPARC number19726594
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Record identifierec0d25a8-5bf8-4d63-a688-af9fc6355611
Record created2012-05-11
Record modified2016-05-10
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