SERS assisted ultra-fast peptidic screening: a new tool for drug discovery

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DOIResolve DOI: http://doi.org/10.1039/c1nr11293g
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TypeArticle
Journal titleNanoscale
ISSN2040-3364
2040-3372
Volume4
Issue1
Pages113116
AbstractHerein we present a direct label-free ultra-fast method for the identification and classification of the active members of a combinatorial library directly on the solid support used for their synthesis. The method is based on the appropriate functionalization of polyethylene glycol grafted polystyrene (TentaGel®) microbeads with Au@Ag nanoparticles, the use of these materials directly as solid-phase supports for the synthesis of combinatorial libraries of peptides and the subsequent SERS analysis for identification of each peptide on each bead.
Publication date
LanguageEnglish
AffiliationNational Institute for Nanotechnology; National Research Council Canada
Peer reviewedYes
NPARC number21268932
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Record identifierec9ecc64-54b3-48c7-b18f-984e09482665
Record created2013-11-26
Record modified2016-05-09
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