Glycosphingolipid synthesis employing a combination of recombinant glycosyltransferases and an endoglycoceramidase glycosynthase

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DOIResolve DOI: http://doi.org/10.1039/c1cc13885e
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TypeArticle
Journal titleChemCommun
Volume47
Pages1080610808; # of pages: 3
AbstractGlycosynthase mutants of Rhodococcus sp. endo-glycoceramidase II efficiently synthesize complex glycosphingolipids. Glycosyl fluoride donors may be assembled via sequential glycosyltransferase- catalysed glycosylation of lactosyl fluoride. Alternatively, lactosyl fluoride may be coupled to sphingosine prior to subsequent glycosylation steps.
Publication date
LanguageEnglish
AffiliationNRC Institute for Biological Sciences; National Research Council Canada
Peer reviewedYes
NPARC number19258802
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Record identifieree98d354-dd39-4bc2-9acb-51ae4246fcc0
Record created2012-03-08
Record modified2016-05-09
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