Label-free Biosensor Array Based on Silicon-on-Insulator Ring Resonators Addressed Using a WDM Approach

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DOIResolve DOI: http://doi.org/10.1364/OL.35.002771
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TypeArticle
Journal titleOptics Letters
Volume35
Issue16
Pages27712773; # of pages: 3
AbstractWe report a silicon-on-insulator ring resonator biosensor array with one output port, using wavelength division multiplexing as the addressing scheme. With the use of on-chip referencing for environmental drift cancellation, simultaneous monitoring of multiplexed molecular bindings is demonstrated, with a resolution of 0:3 pg=mm2 (40 ag of total mass) for protein concentrations over 4 orders of magnitude down to 20 pM. Reactions are measured over time periods as long as 3 h with high stability.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Microstructural Sciences; NRC Steacie Institute for Molecular Sciences; NRC Institute for Biological Sciences
Peer reviewedYes
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This is a non-NRC publication

"Non-NRC publications" are publications authored by NRC employees prior to their employment by NRC.

NPARC number17379833
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Record identifierfa242fca-d0c8-46d3-84c2-e180e23e1134
Record created2011-03-23
Record modified2016-05-09
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