Silicon photonic wire biosensors: Sensing, instrumentation, and applications

DOIResolve DOI: http://doi.org/10.1109/ICO-IP.2011.5953736
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TypeArticle
Proceedings title2011 ICO International Conference on Information Photonics, IP 2011
Conference2011 ICO International Conference on Information Photonics, IP 2011, 18 May 2011 through 20 May 2011, Ottawa, ON
ISBN9781612843155
Article number5953736
SubjectEase-of-use; Evanescent fields; Grating couplers; Label free; Label-free molecular detection; Molecular binding; Molecular sensing; On chips; Optical couplings; Patterned structure; Photonic wires; Propagation lengths; Sensor chips; Sensor platform; Silicon photonics; Silicon waveguide; Sub-wavelength; Biosensors; Fluidics; Instruments; Photonics; Wire; Sensors
AbstractPhotonic wire evanescent field (PWEF) sensor chips have been developed for multiplexed label free molecular detection. The sensors are made using 260 nm ×450 nm cross-section silicon waveguides folded into spirals less than 200 μm in diameter, but with an overall sensor length of more than a millimeter. The long propagation length gives a response to molecular binding much better than currently available tools for label-free molecular sensing. These sensors can be arrayed at densities up to ten or more per square millimeter. This talk reviews our ongoing work on the photonic wire sensor chip design and layout, on-chip integrated fluidics, optical coupling, and chip interrogation using arrays of grating couplers formed using sub-wavelength patterned structures. The goal is to develop a commercially viable sensor platform by addressing cost-of-instrumentation, cost per measurement, ease-of-use, and by increasing the number of sensors that can be simultaneously monitored. © 2011 IEEE.
Publication date
LanguageEnglish
AffiliationNational Research Council Canada (NRC-CNRC); NRC Institute for Microstructural Sciences; NRC Steacie Institute for Molecular Sciences; Measurement Science and Standards; Human Health Therapeutics
Peer reviewedYes
NPARC number21271116
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Record identifierfa8edc00-f6bc-44a5-b35d-ab78b755b9c9
Record created2014-03-24
Record modified2016-05-09
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