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Wang, N.; Lu, Y.; Pinard, M.; Pilotte, A.; Gilbert, R.; Massie, B.; Brodt, P., "Sustained production of a soluble IGF-I receptor by gutless adenovirus-transduced host cells protects from tumor growth in the liver", Cancer Gene Therapy, 20 (4), 2013, (
Robert, Marc-André; Zeng, Yue; Raymond, Benoît; Desfossé, Laurie; Mairey, Emilie; Tremblay, Jacques P.; Massie, Bernard; Gilbert, Rénald, "Efficacy and site-specificity of adenoviral vector integration mediated by the phage φC31 integrase", Human Gene Therapy Methods, 23 (6), 2012, (
Robert, Marc-André; Lin, Yuanbang; Bendjelloul, Mehdi; Zeng, Yue; Dessolin, Sofien; Broussau, Sophie; Larochelle, Nancy; Nalbantoglu, Josephine; Massie, Bernard; Gilbert, Rénald, "Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors", The Journal of Gene Medicine, 14 (12), 2012, (
Piché, Chantal; Béland, Kathie; Lapierre, Pascal; Massie, Bernard; Alvarez, Fernando, "Different sites of xenoantigen delivery lead to a virally induced late-onset hepatitis in mice through molecular mimicry", Liver International, 31 (9), p.1306-1314, 2011, (
Chitty, David W.; Tremblay, Roger G.; Ribecco-Lutkiewicz, Maria; Haukenfrers, Julie; Zurakowski, Bogdan; Massie, Bernard; Sikorska, Marianna; Bani, Mahmud, "Development of BMP7-producing human cells, using a third generation lentiviral gene delivery system", Journal of Neuroscience Methods, 205 (1), p.17-27, 2011, (
Choi, Young J.; Morel, Lyne; Le François, Teffainie; Bourque, Denis; Bourget, Lucie; Groleau, Denis; Massie, Bernard; Miguez, Carlos B., "Novel, versatile, and tightly regulated expression system for escherichia coli strains", Applied and Environmental Microbiology, 76 (15), 2010, (
Blain, Marilyne; Zeng, Yue; Bendjelloul, Mehdi; Hallauer, Patricia L.; Kumar, Angela; Hastings, Kenneth E.M.; Karpati, George; Massie, Bernard; Gilbert, Rénald, "Strong muscle-specific regulatory cassettes based on multiple copies of the human slow troponin I gene upstream enhancer", Human Gene Therapy, 21 (1), 2010, (
Assouline-Thomas, Beatrice; Pilotte, Amélie; Petropavlovskaia, Maria; Makhlin, Julia; Ding, Jieping; McLeod, David; Hanley, Stephen; Massie, Bernard; Rosenberg, Lawrence, "Production and characterization of the recombinant Islet Neogenesis Associated Protein (rINGAP)", Protein expression and purification, 69 (1), p.1-8, 2010, (
Gaillet, Bruno; Gilbert, Rénald; Broussau, Sophie; Pilotte, Amélie; Malenfant, Félix; Mullick, Alaka; Garnier, Alain; Massie, Bernard, "High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch", Biotechnology and Bioengineering, 106 (2), 2010, (
Dufour, Florent; Sasseville, A. Marie-Josée; Chabaud, Stéphane; Massie, Bernard; Siegel, Richard M.; Langelier, Yves, "The ribonucleotide reductase R1 subunits of herpes simplex virus types 1 and 2 protect cells against TNFα- and FasL-induced apoptosis by interacting with caspase-8", Apoptosis, 16 (3), 2010, (
Caron, Antoine W.; Nicolas, Claire; Gaillet, Bruno; Ba, Ismaïla; Pinard, Maxime; Garnier, Alain; Massie, Bernard; Gilbert, Rénald, "Fluorescent labeling in semi-solid medium for selection of mammalian cells secreting high-levels of recombinant proteins", BMC Biotechnology, 9 (42), 2009, (
Le, Phuong U.; Lenferink, Anne E. G.; Pinard, Maxime; Baardsnes, Jason; Massie, Bernard; O'Connor-McCourt, Maureen D., "Escherichia coli expression and refolding of E/K-coil-tagged EGF generates fully bioactive EGF for diverse applications", Protein Expression and Purification, 64 (2), 2008, (
Hanley, Stephen C.; Pilotte, Amélie; Massie, Bernard; Rosenberg, Lawrence, "Cellular origins of adult human islet in vitro dedifferentiation", Laboratory Investigation, 88 (7), 2008, (
Zeng, Yue; Pinard, Maxime; Jaime, Jaïro; Bourget, Lucie; Le, Phuong Uyen; O'Connor-McCourt, Maureen D.; Gilbert, Rénald; Massie, Bernard, "A ligand-pseudoreceptor system based on de novo designed peptides for the generation of adenoviral vectors with altered tropism", The Journal of Gene Medicine, 10 (4), 2008, (
Broussau, Sophie; Jabbour, Nadine; Lachapelle, Guillaume; Durocher, Yves; Tom, Roseanne; Transfiguracion, Julia; Gilbert, Rénald; Massie, Bernard, "Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture", Molecular Therapy, 16 (3), 2008, (
Gilbert, R.; Broussau, S.; Massie, B., "Protein production using lentiviral vectors", 2007.
Gaillet, Bruno; Gilbert, Renald; Amziani, Rachid; Guilbault, Claire; Gadoury, Christine; Caron, Antoine W.; Mullick, Alaka; Garnier, Alain; Massie, Bernard, "High-Level Recombinant Protein Production in CHO Cells Using an Adenoviral Vector and the Cumate Gene-Switch", 23 (1), 2007, (
Richard, C.; Duivenvoorden, W.; Bourbeau, D.; Massie, B.; Roa, W.; Yau, J.; Th'ng, J., "Sensitivity of 5-fluorouracil-resistant cancer cells to adenovirus suicide gene therapy", 14 (1), 2007, (
Chabaud, Stéphane; Sasseville, A. Marie-Josée; Elahi, Seyyed Mehdy; Caron, Antoine; Dufour, Florent; Massie, Bernard; Langelier, Yves, "The ribonucleotide reductase domain of the R1 subunit of herpes simplex virus type 2 ribonucleotide reductase is essential for R1 antiapoptotic function", Journal of General Virology, 88 , 2007, (
Bourbeau, Denis; Lau, C. J.; Jaime, J.; Koty, Z.; Zehtner, S. P.; Lavoie, G.; Mes-Masson, A-M.; Nalbantoglu, J.; Massie, Bernard, "Improvement of Antitumor Activity b Gene Amplification with a Replicating but Nondisseminating Adenovirus", Cancer Research, 2007, (
Okamba, F. R.; Moreau, E.; Bouh, K. Cheikh Saad; Gagnon, C. A.; Massie, Bernard; Arella, M., "Immune Responses Induced by Replication-Defective Adenovirus Expressing the C-Terminal Portion of the Mycoplasma hyopneumoniae P97 Adhesin", Clinical and Vaccine Immunology, 2007, (
Romieu-Mourez, Raphaëlle; Solis, Mayra; Nardin, Alessandra; Goubau, Delphine; Baron-Bodo, Véronique; Lin, Rongtuan; Massie, Bernard; Salcedo, Margarita; Hiscott, John, "Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages", 66 (21), 2006, (
Ogorelkova, Miroslava; Zwaagstra, John; Elahi, Seyyed Mehdy; Dias, Christel; Guilbaut, Claire; Lo, Rita; Collins, Cathy; Jaramillo, Maria; Mullick, Alaka; O'Connor-McCourt, Maureen; Massie, Bernard, "Adenovirus-delivered antisense RNA and shRNA exhibit different silencing efficiencies for the endogenous transforming growth factor-beta (TGF-beta) type II receptor", Oligonucleotides, 16 (1), 2006, (
Gilbert, R.; Massie, B., "Eukaryotic Virus Vectors", 2006.
Blain, Marilyne; Kumar, Angela; Hastings, Kenneth E.; Karpati, George; Massie, Bernard; Gilbert, Renald, "Muscle Specific and Efficient Transgene Expression Using the Fast and Slow Troponin I Promoters in Cell Culture", p. 125-125, 2006, (
Elvira, George; Massie, Bernard; DesGroseillers, Luc, "The zinc-finger protein ZFR is critical for Staufen 2 isoform specific nucleocytoplasmic shuttling in neurons", 96 (1), 2006, (
Choi, Young J.; Morel, Lyne; Bourque, Denis; Mullick, Alaka; Massie, Bernard; Miguez, Carlos B., "Bestowing inducibility on the cloned methanol dehydrogenase promoter (PmxaF) of Methylobacterium extorquens by applying regulatory elements of Pseudomonas putida F1", 72 (12), 2006, (
Yang, Chun; Gagnon, David; Vachon, Pascal; Tremblay, André; Levy, Emile; Massie, Bernard; Michaud, Jacques L., "Adenoviral-mediated modulation of Sim1 expression in the paraventricular nucleus affects food intake", 26 (26), 2006, (
Xu, J.; Jardin, B.; Tran, R.; Mullick, A.; Massie, B.; Elias, C., "A novel system for enhanced baculovirus mediated transient transgene expression in CHO cells", 2006.
Sasseville, A. Marie-Josée; Caron, Antoine W.; Bourget, Lucie; Klein, Arnaud F.; Dicaire, Marie-Josée; Rouleau, Guy A.; Massie, Bernard; Langelier, Yves; Brais, Bernard, "The dynamism of PABPN1 nuclear inclusions during the cell cycle", Neurobiology of Disease, 23 (3), 2006, (
Mullick, Alaka; Xu, Yan; Warren, René; Koutroumanis, Maria; Guilbault, Claire; Broussau, Sophie; Malenfant, Félix; Bourget, Lucie; Lamoureux, Linda; Lo, Rita; Caron, Antoine W.; Pilotte, Amelie; Massie, Bernard, "The cumate gene-switch: a system for regulated expression in mammalian cells", 6 , p.43, 2006, (
St-Louis, Marie-Claude; Massie, Bernard; Archambault, Denis, "The bovine viral diarrhea virus (BVDV) NS3 protein, when expressed alone in mammalian cells, induces apoptosis which correlates with caspase-8 and caspase-9 activation", 36 (2), 2005, (
Bellemare-Pelletier, Angélique; Tremblay, Jessy; Beaulieu, Sylvie; Boulassel, Mohamed-Rachid; Routy, Jean-Pierre; Massie, Bernard; Lapointe, Réjean; Thibodeau, Jacques, "HLA-DO transduced in human monocyte-derived dendritic cells modulates MHC class II antigen processing", Journal of Leukocyte Biology, 78 , 2005, (
Corbeil-Girard, Louis-Philippe; Klein, Arnaud F.; Sasseville, A. Marie-Josée; Lavoie, Hugo; Dicaire, Marie-Josée; Saint-Denis, Anik; Pagé, Martin; Duranceau, André; Codère, François; Bouchard, Jean-Pierre; Karpati, George; Rouleau, Guy A.; Massie, Bernard; Langelier, Yves; Brais, Brais, "PABPN1 overexpression leads to upregulation of genes encoding nuclear proteins that are sequestered in oculopharyngeal muscular dystrophy nuclear inclusions", Neurobiology of Disease, 18 (3), 2005, (
Kheyar, Ali; Jabrane, Ahmed; Zhu, Chengru; Cléroux, Patrick; Massie, Bernard; Dea, Serge; Gagnon, Carl A., "Alternative codon usage of PRRS virus ORF5 gene increases eucaryotic expression of GP5 glycoprotein and improves immune response in challenged pigs", Vaccine, 23 (31), 2005, (
Bourbeau, Denis; Lavoie, Geneviève; Nalbantoglu, Josephine; Massie, Bernard, "Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status", 6 (12), 2004, (
Mullick, Alaka; Elias, Miria; Picard, Serge; Bourget, Lucie; Jovcevski, Orce; Gauthier, Susan; Tuite, Ashleigh; Harakidas, Penelope; Bihun, Craig; Massie, Bernard; Gros, Philippe, "Dysregulated inflammatory response to Candida albicans in a C5-deficient mouse strain", 72 (10), 2004, (
Mullick, Alaka; Elias, Miria; Harakidas, Penelope; Marcil, Anne; Whiteway, Malcolm; Ge, Bing; Hudson, Thomas; Caron, Antoine; Bourget, Lucie; Picard, Serge; Jovcevski, Orce; Massie, Bernard; Thomas, David, "Gene Expression in HL60 Granulocytoids and Human Polymorphonuclear Leukocytes Exposed to Candida albicans{dagger}", Acoustics, Speech, and Signal Processing Newsletter, IEEE, 72 (1), 2004, (
Ogorelkova, Miroslava; Elahi, Seyyed Mehdy; Gagnon, David; Massie, Bernard, "DNA delivery to cells in culture: generation of adenoviral libraries for high-throughput functional screening", Gene Delivery to Mammalian Cells : Volume 2: Viral Gene Transfer Techniques Methods in Molecular Biology, 2004, (
Roduit, R; Nolan, C; Alarcon, C; Moore, P; Barbeau, A; Delghingaro-Augusto, V; Przybykowski, E; Morin, J; Masse, F; Massie, B; Ruderman, N; Rhodes, C; Poitout, V; Prentki, M, "A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli", 53 (4), 2004, (
Wosik, Karolina; Antel, Jack; Kuhlmann, Tanja; Bruck, Wolfgang; Massie, Bernard; Nalbantoglu, Josephine, "Oligodendrocyte injury in multiple sclerosis: a role for p53", 85 (3), 2003, (
Fortin, Marylène; Lepine, Manon; Page, Martin; Osteen, Kevin; Massie, Bernard; Hugo, Patrice; Steff, Ann-Muriel, "An improved mouse model for endometriosis allows noninvasive assessment of lesion implantation and development", 80 Suppl 2 , 2003, (
Bourbeau, Denis; Zeng, Yue; Massie, Bernard, "Virus-based vectors for gene expression in mammalian cells: adenovirus", Gene Transfer and Expression in Mammalian Cells New Comprehensive Biochemistry, 2003, (
Brousseau, R; Jabbour, N; Lachapelle, G; Xu, Y; Mullick, A; Gilbert, R; Massie, B, "Development of stable pakaging cell lines for the production of regulated cSIN lentiviral vectors. 6iéme Colloque de l'Association de thérapie génique du Québec, Montréal, QC Oct. 2003", 2003.
Gagnon, C. A.; Lachapelle, G.; Langelier, Y.; Massie, B.; Dea, S., "Adenoviral-expressed GP5 of porcine respiratory and reproductive syndrome virus differs in its cellular maturation from the authentic viral protein but maintains known biological functions", 148 (5), 2003, (
Chabaud, Stéphane; Lambert, Herman; Sasseville, A. Marie-Josée; Lavoie, Hugo; Guilbault, Claire; Massie, Bernard; Landry, Jacques; Langelier, Yves, "The R1 subunit of herpes simplex virus ribonucleotide reductase has chaperone-like activity similar to Hsp27", FEBS Letters, 545 , 2003, (
Langelier, Yves; Bergeron, Stéphane; Chabaud, Stéphane; Lippens, Julie; Guilbault, Claire; Sasseville, A. Marie-Josée; Denis, Stéphan; Mosser, Dick D.; Massie, Bernard, "The R1 subunit of herpes simplex virus ribonucleotide reductase protects cells against apoptosis at, or upstream of, caspase-8 activation", 83 , 2002.
Larochelle, Nancy; Oualikene, Wahiba; Dunant, Patrick; Massie, Bernard; Karpati, George; Nalbantoglu, Josephine; Lochmuller, Hanns, "The short MCK1350 promoter/enhancer allows for sufficient dystrophin expression in skeletal muscles of mdx mice", 292 (3), 2002, (
Elahi, S. M.; Oualikene, W.; Naghdi, L.; O'Connor-McCourt, M. D.; Massie, B., "Adenovirus-based libraries: efficient generation of recombinant adenoviruses by positive selection with the adenovirus protease", Gene Therapy, 9 (18), 2002, (
Belkhiri, Abbes; Lytvyn, Viktoria; Guilbault, Claire; Bourget, Lucie; Massie, Bernard; Nägler, Dorit K.; Ménard, Robert, "A noninvasive cell-based assay for monitoring proteolytic activity within a specific subcellular compartment", Analytical Biochemistry, 306 (2), 2002, (
Larocque, Daniel; Pilotte, Julie; Chen, Taiping; Cloutier, Frank; Massie, Bernard; Pedraza, Liliana; Couture, Réjean; Lasko, Paul; Almazan, Guillermina; Richard, Stéphane, "Nuclear Retention of MBP mRNAS in the Quaking viable Mice", 36 (5), 2002, (
Gagnon, C. A.; Langelier, Y.; Massie, B.; Dea, S., "Biochemical properties and processing of the three major structural proteins of PRRS virus expressed by recombinant adenoviruses. Structural, functional and community aspects.", Advances in Experimental Medicine & Biology, 494 , 2001.
Gilbert, Rénald; Nalbantoglu, Joséphine; Howell, John McC.; Davies, Linda; Fletcher, Susan; Amalfitano, Andrea; Petrof, Basil J.; Kamen, Amine; Massie, Bernard; Karpati, George, "Dystrophin expression in muscle following gene transfer with a fully deleted ("Gutted") adenovirus Is markedly improved by trans-acting adenoviral gene products", Human Gene Therapy, 12 (14), 2001, (
Nakagawa, Shinsaku; Massie, Bernard; Hawley, Robert G., "Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential", 13 (1), 2001, (
Campeau, P.; Chapdelaine, P.; Seigneurin-Venin, S.; Massie, B.; Tremblay, J., "Transfection of large plasmids in primary human myoblasts", Gene Ther, 8 (18), 2001.
Gabai, Vladimir L.; Yaglom, Julia A.; Volloch, Vladimir; Meriin, Anatoli B.; Force, Thomas; Koutroumanis, Maria; Massie, Bernard; Mosser, Dick D.; Sherman, Michael Y., "Hsp72-mediated suppression of c-Jun N-terminal kinase is implicated in development of tolerance to caspase-independent cell death", 20 (18), 2000.
Atwal, Jasvinder K.; Massie, Bernard; Miller, Freda D.; Kaplan, David R., "The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase", 27 (2), 2000, (
Cho, Won-Kyung; Ebihara, Satoru; Nalbantoglu, Josephine; Gilbert, Renald; Massie, Bernard; Holland, Paul; Karpati, George; Petrof, Basil J., "Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route", 11 (5), 2000.
Mercille, Sylvain; Johnson, Mark; Lanthier, Stephane; Kamen, Amine A.; Massie, Bernard, "Understanding factors that limit the productivity of suspension-based perfusion cultures operated at high medium renewal rates", 67 (4), 2000.
Massie, B., "Production des vecteurs adénoviraux", La Thérapie Génique, 2000.
Mosser, Dick D.; Caron, Antoine W.; Bourget, Lucie; Meriin, Anatoli B.; Sherman, Michael Y.; Morimoto, Richard I.; Massie, Bernard, "The chaperone function of hsp70 is required for protection against stress-induced apoptosis", 20 (19), 2000.
Ebihara, Satoru; Guibinga, Ghiabe-Henri; Gilbert, Renald; Nalbantoglu, Josephine; Massie, Bernard; Karpati, George; Petrof, Basil J., "Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice", Physiological Genomics, 3 (3), 2000.
Hou, Sheng T.; Callaghan, Debbie; Fournier, Marie-Christine; Hill, Irene; Kang, Liping; Massie, Bernard; Morley, Paul; Murray, Christine; Rasquinha, Ingrid; Slack, Ruth; MacManus, John P., "The transcription factor E2F1 modulates apoptosis of neurons", Journal of Neurochemistry, 75 (1), 2000, (
Oualikene, Wahiba; Lamoureux, Linda; Weber, Joseph M.; Massie, Bernard, "Protease-deleted adenovirus vectors and complementing cell lines: potential applications of single-round replication mutants for vaccination and gene therapy", 11 (9), 2000.
Mullick, A.; Massie, B., "Transcription, translation and the control of gene expression", The Encyclopedia of Cell Technologies, 2000.
Oualikene, W.; Massie, B., "Adenovirus vectors in functional genomics", Cell Engineering Vol 2, 2000.
Caron, Antoine W.; Massie, Bernard; Mosser, Dick D., "Use of a micromanipulator for high-efficiency cloning of cells co-expressing fluorescent proteins", Methods in Cell Science, 22 (2), 2000, (
Gilbert, Rénald; Nalbantoglu, Josephine; Petrof, Basil J.; Ebihara, Satoru; Guibinga, Ghiabe-Henri; Tinsley, Jonathon M.; Kamen, Amine; Massie, Bernard; Davies, Kay E.; Karpati, George, "Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles", Human Gene Therapy, 10 (8), 1999, (
Elahi, Seyyed Mehdy; Shen, Shi-Hsiang; Talbot, Brian Geoffrey; Massie, Bernard; Harpin, Serge; Elazhary, Youssef, "Recombinant adenoviruses expressing the E2 protein of bovine viral diarrhea virus induce humoral and cellular immune responses", 177 (1), 1999.
Elahi, Seyyed Mehdy; Shen, Shi-Hsiang; Talbot, Brian Geoffrey; Massie, Bernard; Harpin, Serge; Elazhary, Youssef, "Induction of humoral and cellular immune responses against the nucleocapsid of bovine viral diarrhea virus by an adenovirus vector with an inducible promoter", 261 (1), 1999.
Mercille, Sylvain; Massie, Bernard, "Apoptosis-resistant E1B-19K-expressing NS/0 myeloma cells exhibit increased viability and chimeric antibody productivity under perfusion culture conditions", Biotechnology and Bioengineering, 63 (5), 1999.
Mercille, Sylvain; Jolicoeur, Pierre; Gervais, Christian; Paquette, Denis; Mosser, Dick D.; Massie, Bernard, "Dose-dependent reduction of apoptosis in nutrient-limited cultures of NS/0 myeloma cells transfected with the E1B-19K adenoviral gene", 63 (5), 1999.
Massie, Bernard; Mosser, Dick D.; Koutroumanis, Maria; Vitté-mony, Isabelle; Lamoureux, Linda; Couture, France; Paquet, Luc; Guilbault, Claire; Dionne, Julie; Chahla, Dounia; Jolicoeur, Pierre; Langelier, Yves, "New adenovirus vectors for protein production and gene transfer", Cytotechnology, 28 , 1998.
Mercille, Sylvain; Massie, Bernard, "Apoptosis-resistant NS/0 E1B-19K myelomas exhibit increased viability and chimeric antibody productivity under cell cycle modulating conditions", Cytotechnology, 28 , 1998.
Yang, L.; Lochmuller, H.; Luo, J.; Massie, B.; Nalbantoglu, J.; Karpati, G.; Petrof, B. J., "Adenovirus-mediated dystrophin minigene transfer improves muscle strength in adult dystrophic (MDX) mice", 5 (3), 1998.
Gonin, P.; Mardassi, H.; Gagnon, C. A.; Massie, B.; Dea, S., "A nonstructural and antigenic glycoprotein is encoded by ORF3 of the IAF-Klop strain of porcine reproductive and respiratory syndrome virus", 143 (10), 1998.
Côté, Johanne; Garnier, Alain; Massie, Bernard; Kamen, Amine, "Serum-free production of recombinant proteins and adenoviral vectors by 293SF-3F6 cells", Biotechnology and Bioengineering, 59 (5), 1998.
Guibinga, Ghiabe-Henri; Lochmuller, Hanns; Massie, Bernard; Nalbantoglu, Josephine; Karpati, George; Petrof, Basil J., "Combinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles", 72 (6), 1998.
Massie, Bernard; Couture, France; Lamoureux, Linda; Mosser, Dick D.; Guilbault, Claire; Jolicoeur, Pierre; Belanger, François; Langelier, Yves, "Inducible overexpression of a toxic protein by an adenovirus vector with a tetracycline-regulatable expression cassette", Journal of Virology, 72 (3), 1998.
Gilbert, Rénald; Nalbanoglu, Josephine; Tinsley, Jonathon M.; Massie, Bernard; Davies, Kay E.; Karpati, George, "Efficient utrophin expression following adenovirus gene transfer in dystrophic muscle", Biochemical and Biophysical Research Communications, 242 (1), 1998, (
Mardassi, Helmi; Gonin, Patrick; Gagnon, Carl A.; Massie, Bernard; Dea, Serge, "A subset of porcine reproductive and respiratory syndrome virus GP3 glycoprotein is released into the culture medium of cells as a non-virion-associated and membrane-free (soluble) form", 72 (8), 1998.
Howell, J. M.; Lochmuller, H.; O'Hara, A.; Fletcher, S.; Kakulas, B. A.; Massie, B.; Nalbantoglu, J.; Karpati, G., "High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression", 9 (5), 1998.
Langelier, Yves; Champoux, Louise; Hamel, Martine; Guilbault, Claire; Lamarche, Nathalie; Gaudreau, Pierrette; Massie, Bernard, "The R1 subunit of herpes simplex virus ribonucleotide reductase is a good substrate for host cell protein kinases but is not itself a protein kinase", Journal of Biological Chemistry, 273 (3), 1998.
Volloch, Vladimir; Mosser, Dick D.; Massie, Bernard; Sherman, Michael Y., "Reduced thermotolerance in aged cells results from a loss of an hsp72-mediated control of JNK signaling pathway", 3 (4), 1998.
Gervais, C.; Paquette, D.; Burns-Tardif, A.; Martin, L.; Massie, B., "Development of high output expression vectors for Itibody production in mammalian cells", Ninth Annual Meeting of the Japanese Association for Animal Cell Technology, September 01-04, 1996, Yokohama, Japan, Proceedings of the Ninth Annual Meeting of the Japanese Association for Animal Cell Technology, p. 349-354, 1998.
Durham, H. D.; Alonso-Vanegas, M. A.; Sadikot, A. F.; Zhu, L.; Lochmuller, H.; Massie, B.; Nalbantoglu, J.; Karpati, G., "The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer", 8 , 1997.
Zhao, Ji-En; Lochmüller, Hanns; Nalbantoglu, Josephine; Allen, Carol; Prescott, Stephen; Massie, Bernard; Karpati, George, "Study of adenovirus-mediated dystrophin minigene transfer to skeletal muscle by combined microscopic display of adenoviral DNA and dystrophin", Human Gene Therapy, 8 (13), 1997, (
Jani, A.; Lochmuller, H.; Acsadi, G.; Simoneau, M.; Huard, J.; Garnier, A.; Karpati, G.; Massie, B., "Generation, validation, and large scale production of adenoviral recombinants with large size inserts such as a 6.3 kb human dystrophin cDNA", 64 (2), 1997.
Mosser, Dick D.; Caron, Antonie W.; Bourget, Lucie; Denis-Larose, Claude; Massie, Bernard, "Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis", 17 (9), 1997.
Mosser, D. D.; Caron, A. W.; Bourget, L.; Jolicoeur, P.; Massie, B., "Use of a dicistronic expression cassette encoding the green fluorescent protein for the screening and selection of cells expressing inducible gene products", Biotechniques, 22 (1), 1997.
Nadeau, I.; Garnier, A.; Cote, J.; Massie, B.; Chavarie, C.; Kamen, A., "Improvement of recombinant protein production with the human adenovirus/293S expression system using fed-batch strategies", Biotechnology and Bioengineering, 51 (6), 1996.
Lochmüller, H.; Petrof, B.J.; Pari, G.; Larochelle, N.; Dodelet, V.; Wang, Q.; Allen, C.; Prescott, S.; Massie, B.; Nalbantoglu, J.; Karpati, G., "Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice", Gene Therapy, 3 (8), 1996.
Mardassi, Helmi; Massie, Bernard; Dea, Serge, "Intracellular synthesis, processing, and transport of proteins encoded by ORFs 5 to 7 of porcine reproductive and respiratory syndrome virus", Virology, 221 (1), 1996.
Paquet, Luc; Massie, Bernard; Mains, Richard E., "Proneuropeptide Y processing in large dense-core vesicles: manipulation of prohormone convertase expression in sympathetic neurons using adenoviruses", 16 (3), 1996.
Durham, Heather D.; Lochmuller, Hanns; Jani, Agnes; Acsadi, Gyula; Massie, Bernard; Karpati, George, "Toxicity of replication-defective adenoviral recombinants in dissociated cultures of nervous tissue", 140 (1), 1996.
Lamarche, Nathalie; Matton, Gilles; Massie, Bernard; Fontecave, Marc; Atta, Mohamed; Dumas, France; Gaudreau, Pierrette; Langelier, Yves, "Production of the R2 subunit of ribonucleotide reductase from herpes simplex virus with prokaryotic and eukaryotic expression systems: higher activity of R2 produced by eukaryotic cells related to higher iron-binding capacity", 320( Pt 1) , 1996.
Trudel, P.; Provost, S.; Massie, B.; Chartrand, P.; Wall, L., "pGATA: a positive selection vector based on the toxicity of the transcription factor GATA-1 to bacteria", 20 (4), 1996.
Acsadi, Gyula; Lochmuller, Hanns; Jani, Agnes; Huard, Johnny; Massie, Bernard; Prescott, Stephen; Simoneau, Maude; Petrof, Basil J.; Karpati, George, "Dystrophin expression in muscles of mdx mice after adenovirus-mediated in vivo gene transfer", 7 (2), 1996.
Petrof, B. J.; Lochmuller, H.; Massie, B.; Yang, L.; Macmillan, C.; Zhao, J. E.; Nalbantoglu, J.; Karpati, G., "Impairment of force generation after adenovirus-mediated gene transfer to muscle is alleviated by adenoviral gene inactivation and host CD8+ T cell deficiency", 7 (15), 1996.
Johnson, Mark; Lanthier, Stéphane; Massie, Bernard; Lefebvre, Gilles; Kamen, Amine A., "Use of the Centritech Lab centrifuge for perfusion culture of hybridoma cells in protein-free medium", 12 (6), 1996.
Tom, R. L.; Debanne, M. T.; Bedard, C.; Caron, A. W.; Massie, B.; Kamen, A., "Improved yields of the extracellular domain of the epidermal growth factor receptor produced using the baculovirus expression system by medium replacement following infection", Applied Microbiology and Biotechnology, 44 , 1995.
Tom, Rosanne L.; Caron, Antoine W.; Massie, Bernard; Kamen, Amine A., "Scale-Up of Recombinant Virus and Protein Production in Stirred-Tank Reactors", Methods Mol Biol, 1995.
Dayan, Alain; Bertrand, Richard; Beauchemin, Myriam; Chahla, Dounia; Mamo, Aline; Filion, Mario; Skup, Daniel; Massie, Bernard; Jolivet, Jacques, "Cloning and characterization of the human 5,10-methenyltetrahydrofolate synthetase-encoding cDNA", Gene, 165 (2), 1995.
Acsadi, G.; Massie, B.; Jani, A., "Adenovirus-mediated gene transfer into striated muscles", Journal of Molecular Medicine, 73 (4), 1995.
Huard, Johnny; Lochmuller, Hanns; Acsadi, Gyula; Jani, Agnes; Holland, Paul; Guerin, Claude; Massie, Bernard; Karpati, George, "Differential short-term transduction efficiency of adult versus newborn mouse tissues by adenoviral recombinants", Experimental and Molecular Pathology, 62 (2), 1995.
Massie, Bernard; Dionne, Julie; Lamarche, Nathalie; Fleurent, Johanne; Langelier, Yves, "Improved adenovirus vector provides herpes simplex virus ribonucleotide reductase R1 and R2 subunits very efficiently", Nature Biotechnology, 13 (6), 1995.
Petrof, B. J.; Acsadi, G.; Jani, A.; Massie, B.; Bourdon, J.; Matusiewicz, N.; Yang, L.; Lochmuller, H.; Karpati, G., "Efficiency and functional consequences of adenovirus-mediated in vivo gene transfer to normal and dystrophic (mdx) mouse diaphragm", Am J Respir Cell Mol Biol, 13 (5), 1995.
Lochmuller, H.; Petrof, B. J.; Allen, C.; Prescott, S.; Massie, B.; Karpati, G., "Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice", Acoustics, Speech, and Signal Processing Newsletter, IEEE, 213 (2), 1995.
Huard, J.; Lochmuller, H.; Acsadi, G.; Jani, A.; Massie, B.; Karpati, G., "The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants", Gene Ther, 2 (2), 1995.
Alkhatib, Ghalib; Shen, Shi-Hsiang; Briedis, Dalius; Richardson, Christopher; Massie, Bernard; Weinberg, Randall; Smith, Darlene; Taylor, Jill; Paoletti, Enzo; Roder, John, "Functional analysis of N-linked glycosylation mutants of the measles virus fusion protein synthesized by recombinant vaccinia virus vectors", Journal of Virology, 68 (3), 1994.
Acsadi, Gyula; Jani, Agnes; Massie, Bernard; Simoneau, Maude; Holland, Paul; Blaschuk, Katherine; Karpati, George, "A differential efficiency of adenovirus-mediated in vivo gene transfer into skeletal muscle cells of different maturity", Hum Mol Genet, 3 (4), 1994.
Mercille, S.; Johnson, M.; Bourget, L.; Lemieux, R.; Massie, B., "Process development and kinetic analysis of a protein-free hybridoma perfusion system", 1994.
Mercille, Sylvain; Massie, Bernard, "Induction of Apoptosis in Nutrient-Deprived Cultures of Hybridoma and Myeloma Cells", 44 , 1994.
Huard, Johnny; Acsadi, Gyula; Jani, Agnes; Massie, Bernard; Karpati, George, "Gene transfer into skeletal muscles by isogenic myoblasts", Hum Gene Ther, 5 (8), 1994.
Mercille, Sylvain; Massie, Bernard, "Induction of apoptosis in oxygen-deprived cultures of hybridoma cells", Cytotechnology, 15 , 1994.
Lochmuller, H.; Jani, A.; Huard, J.; Prescott, S.; Simoneau, M.; Massie, B.; Karpati, G.; Acsadi, G., "Emergence of early region 1-containing replication-competent adenovirus in stocks of replication-defective adenovirus recombinants (delta E1 + delta E3) during multiple passages in 293 cells", Hum Gene Ther, 5 (12), 1994.
Mercille, Sylvain; Johnson, Mark; Lemieux, Réal; Massie, Bernard, "Filtration-Based Perfusion by Hybridoma Cultures in Protein-Free Medium: Reduction of Membrane Fouling my Medium Supplementation with DNase 1", 43 , 1994.
Mosser, Dick D.; Massie, Bernard, "Genetically engineering mammalian cell lines for increased viability and productivity", Biotechnology Advances, 12 , 1994.
Lamarche, Nathalie; Gaudreau, Pierrette; Massie, Bernard; Langelier, Yves, "Affinity of synthetic peptides for the HSV-2 ribonucleotide reductase R1 subunit measured with an iodinated photoaffinity peptide", Anal Biochem, 220 (2), 1994.
Bedard, C.; Kamen, A.; Tom, R.; Massie, B., "Maximization of recombinant protein yield in the insect cell/baculovirus system by one-time addition of nutrients to high-density batch cultures", Cytotechnology, 15 , 1994.
Caron, Antoine W.; Tom, Rosanne L.; Kamen, Amine A.; Massie, Bernard, "Baculovirus expression system scaleup by perfusion of high-density Sf-9 cell cultures", Biotechnology and Bioengineering, 43 (9), 1994, (
Caron, Antoine W.; Archambault, Jean; Massie, Bernard, "High-level recombinant protein production in bioreactors using the baculovirus-insect cell expression system", Biotechnology and Bioengineering, 36 (11), 1990, (
Cote, J.; Couture, F.; Bourget, L.; Gamier, A.; Massie, B.; Kamen, A., "Bioprocess development of ADYproduction in SFM by 293SF cells using the green fluorescente protein as reporter gene", Williamsburg Bioprocessing conference, November 18-21, 1996.
Nadeau, I.; Gamier, A.; Cote, J.; Massie, B.; Chavarie, C.; Kamen, A., "Fedbatch productions of recombinant adenovirus vectors in 2935 cells", Cell Culture Engineering V, San Diego, January 28-February 02, 1996.