Government of Canada
Symbol of the Government of Canada

Common menu bar links

Robert, Marc-André; Lin, Yuanbang; Bendjelloul, Mehdi; Zeng, Yue; Dessolin, Sofien; Broussau, Sophie; Larochelle, Nancy; Nalbantoglu, Josephine; Massie, Bernard; Gilbert, Rénald, "Strength and muscle specificity of a compact promoter derived from the slow troponin I gene in the context of episomal (gutless adenovirus) and integrating (lentiviral) vectors", The Journal of Gene Medicine, 14 (12), 2012, (
Larochelle, Nancy; Teng, Qingshan; Gilbert, Rénald; Deol, Jatinderpal R.; Karpati, George; Holland, Paul C.; Nalbantoglu, Josephine, "Modulation of coxsackie and adenovirus receptor expression for gene transfer to normal and dystrophic skeletal muscle", Journal of Gene Medicine, 12 (3), 2010, (
Lu, Yifan; Tian, Chai; Danialou, Gawiyou; Gilbert, Rénald; Petrof, Basil J.; Karpati, George; Nalbantoglu, Josephine, "Targeting artificial transcription factors to the utrophin A promoter : Effects on dystrophic pathology and muscle function", Journal Of Biological Chemistry, 283 (50), 2008, (
Durocher, Y. (Yves); Pham, P. L.; St-Laurent, Gilles; Jacob, Danielle; Cass, Brian; Chahal, Parminder; Lau, C. J.; Nalbantoglu, J.; Kamen, Amine, "Scalable serum-free production of recombinant adeno-associated virus type 2 b transfection of 293 suspension cells", Journal of Virological Methods, 144 , 2007, (
Deol, Jatinderpal R.; Danialou, Gawiyou; Larochelle, Nancy; Bourget, Mylène; Moon, Joon-Shik; Liu, An-Bang; Gilbert, Rénald; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George, "Successful compensation for dystrophin deficiency by a helper-dependent adenovirus expressing full-length utrophin", Molecular Therapy, 15 (10), 2007, (
Bourbeau, Denis; Lau, C. J.; Jaime, J.; Koty, Z.; Zehtner, S. P.; Lavoie, G.; Mes-Masson, A-M.; Nalbantoglu, J.; Massie, Bernard, "Improvement of Antitumor Activity b Gene Amplification with a Replicating but Nondisseminating Adenovirus", Cancer Research, 2007, (
Deol, Jatinderpal R.; Gilbert, Renald; Danialou, Gawiyou; Bourget, Mylene; Moon, Joon-Shik; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George, "Gene Therapy for Duchenne Muscular Dystrophy Using a Gutted Adenovirus Expressing Utrophin", p. 354-355, 2006, (
Danialou, Gawiyou; Comtois, Alain; Matecki, Stefan; Nalbantoglu, Josephine; Karpati, George; Gilbert, Rénald; Geoffroy, Pascale; Gilligan, Sandra; Tanguay, Jean-Francois; Petrof, Basil, "Optimization of regional intraarterial naked DNA-mediated transgene delivery to skeletal muscles in a large animal model", Molecular Therapy, 11 (2), 2005, (
Waheed, Ishrat; Gilbert, Rénald; Nalbantoglu, Josephine; Guibinga, Ghiabe H.; Petrof, Basil J.; Karpati, George, "Factors associated with induced chronic inflammation in mdx skeletal muscle cause posttranslational stabilization and augmentation of extrasynaptic sarcolemmal utrophin", Human Gene Therapy, 16 (4), 2005, (
Bourbeau, Denis; Lavoie, Geneviève; Nalbantoglu, Josephine; Massie, Bernard, "Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status", 6 (12), 2004, (
Dudley, Roy; Lu, Yifan; Gilbert, Rénald; Matecki, Stefan; Nalbantoglu, Josephine; Petrof, Basil; Karpati, George, "Sustained Improvement of Muscle Function One Year After Full-Length Dystrophin Gene Transfer into mdx Mice by a Gutted Helper-Dependent Adenoviral Vector", Human Gene Therapy, 15 (2), 2004, (
Matecki, Stefan; Dudley, Roy W. R.; Divangahi, Maziar; Gilbert, Renald; Nalbantoglu, Josephine; Karpati, George; Petrof, Basil J., "Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes", American Journal of Physiology: Lung Cellular and Molecular Physiology, 287 (3), 2004, (
Molnar, Maria J.; Gilbert, Rénald; Lu, Yifan; Liu, An-Bang; Guo, Athena; Larochelle, Nancy; Orlopp, Kristian; Lochmuller, Hanns; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George, "Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse muscles", Molecular Therapy, 10 (3), 2004, (
Wosik, Karolina; Antel, Jack; Kuhlmann, Tanja; Bruck, Wolfgang; Massie, Bernard; Nalbantoglu, Josephine, "Oligodendrocyte injury in multiple sclerosis: a role for p53", 85 (3), 2003, (
Gilbert, Rénald; Dudley, Roy; Liu, An-Bang; Petrof, Basil; Nalbantoglu, Josephine; Karpati, George, "Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin", Hum. Mol. Genet., 12 (11), 2003, (
Gilbert, Rénald; Liu, An-Bang; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George, "Improved Performance of a Fully Gutted Adenovirus Vector Containing Two Full-Length Dystrophin cDNAs Regulated by a Strong Promoter", Molecular Therapy, 6 (4), 2002, (
Danialou, Gawiyou; Comtois, Alain; Dudley, Roy; Nalbantoglu, Josephine; Gilbert, Rénald; Karpati, George; Jones, David H.; Petrof, Basil J., "Ultrasound increases plasmid-mediated gene transfer to dystrophic muscles without collateral damage", Molecular Therapy, 6 (5), 2002.
Larochelle, Nancy; Oualikene, Wahiba; Dunant, Patrick; Massie, Bernard; Karpati, George; Nalbantoglu, Josephine; Lochmuller, Hanns, "The short MCK1350 promoter/enhancer allows for sufficient dystrophin expression in skeletal muscles of mdx mice", 292 (3), 2002, (
Gilbert, Rénald; Nalbantoglu, Joséphine; Howell, John McC.; Davies, Linda; Fletcher, Susan; Amalfitano, Andrea; Petrof, Basil J.; Kamen, Amine; Massie, Bernard; Karpati, George, "Dystrophin expression in muscle following gene transfer with a fully deleted ("Gutted") adenovirus Is markedly improved by trans-acting adenoviral gene products", Human Gene Therapy, 12 (14), 2001, (
Cho, Won-Kyung; Ebihara, Satoru; Nalbantoglu, Josephine; Gilbert, Renald; Massie, Bernard; Holland, Paul; Karpati, George; Petrof, Basil J., "Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route", 11 (5), 2000.
Ebihara, Satoru; Guibinga, Ghiabe-Henri; Gilbert, Renald; Nalbantoglu, Josephine; Massie, Bernard; Karpati, George; Petrof, Basil J., "Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice", Physiological Genomics, 3 (3), 2000.
Gilbert, Rénald; Nalbantoglu, Josephine; Petrof, Basil J.; Ebihara, Satoru; Guibinga, Ghiabe-Henri; Tinsley, Jonathon M.; Kamen, Amine; Massie, Bernard; Davies, Kay E.; Karpati, George, "Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles", Human Gene Therapy, 10 (8), 1999, (
Yang, L.; Lochmuller, H.; Luo, J.; Massie, B.; Nalbantoglu, J.; Karpati, G.; Petrof, B. J., "Adenovirus-mediated dystrophin minigene transfer improves muscle strength in adult dystrophic (MDX) mice", 5 (3), 1998.
Guibinga, Ghiabe-Henri; Lochmuller, Hanns; Massie, Bernard; Nalbantoglu, Josephine; Karpati, George; Petrof, Basil J., "Combinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles", 72 (6), 1998.
Howell, J. M.; Lochmuller, H.; O'Hara, A.; Fletcher, S.; Kakulas, B. A.; Massie, B.; Nalbantoglu, J.; Karpati, G., "High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression", 9 (5), 1998.
Durham, H. D.; Alonso-Vanegas, M. A.; Sadikot, A. F.; Zhu, L.; Lochmuller, H.; Massie, B.; Nalbantoglu, J.; Karpati, G., "The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer", 8 , 1997.
Karpati, George; Gilbert, Rénald; Petrof, Basil J.; Nalbantoglu, Josephine, "Gene therapy research for Duchenne and Becker muscular dystrophies", Current Opinion in Neurology, 10 , 1997, (
Zhao, Ji-En; Lochmüller, Hanns; Nalbantoglu, Josephine; Allen, Carol; Prescott, Stephen; Massie, Bernard; Karpati, George, "Study of adenovirus-mediated dystrophin minigene transfer to skeletal muscle by combined microscopic display of adenoviral DNA and dystrophin", Human Gene Therapy, 8 (13), 1997, (
Lochmüller, H.; Petrof, B.J.; Pari, G.; Larochelle, N.; Dodelet, V.; Wang, Q.; Allen, C.; Prescott, S.; Massie, B.; Nalbantoglu, J.; Karpati, G., "Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice", Gene Therapy, 3 (8), 1996.
Petrof, B. J.; Lochmuller, H.; Massie, B.; Yang, L.; Macmillan, C.; Zhao, J. E.; Nalbantoglu, J.; Karpati, G., "Impairment of force generation after adenovirus-mediated gene transfer to muscle is alleviated by adenoviral gene inactivation and host CD8+ T cell deficiency", 7 (15), 1996.
Deol, J. R.; Gilbert, R.; Bourget, M.; Danialou, G.; Moon, J.; Petrof, B. J.; Nalbantoglu, J.; Karpati, G., "Adenovirus-Mediated Utrophin Gene Delivery as a Therapy for Duchenne Muscular Dystrophy", The 58th Annual Meeting of American Academy of Neurology - San Diego, 2006.