NRC Publications Archive - "Nalbantoglu, J."

Modulation of coxsackie and adenovirus receptor expression for gene transfer to normal and dystrophic skeletal muscle

Fri, 05 Nov 2010 08:02:11 +0000

Modulation of coxsackie and adenovirus receptor expression for gene transfer to normal and dystrophic skeletal muscle
Larochelle, Nancy; Teng, Qingshan; Gilbert, Rénald; Deol, Jatinderpal R.; Karpati, George; Holland, Paul C.; Nalbantoglu, Josephine
Journal of Gene Medicine, 12 (3), 2010, p. 266-275

Targeting artificial transcription factors to the utrophin A promoter : Effects on dystrophic pathology and muscle function

Fri, 02 Oct 2009 09:01:09 +0000

Targeting artificial transcription factors to the utrophin A promoter : Effects on dystrophic pathology and muscle function
Lu, Yifan; Tian, Chai; Danialou, Gawiyou; Gilbert, Rénald; Petrof, Basil J.; Karpati, George; Nalbantoglu, Josephine
Journal Of Biological Chemistry, 283 (50), 2008-10-21, p. 34720-34727

Scalable serum-free production of recombinant adeno-associated virus type 2 b transfection of 293 suspension cells

Wed, 03 Jun 2009 10:36:27 +0000

Scalable serum-free production of recombinant adeno-associated virus type 2 b transfection of 293 suspension cells
Durocher, Y. (Yves); Pham, P. L.; St-Laurent, Gilles; Jacob, Danielle; Cass, Brian; Chahal, Parminder; Lau, C. J.; Nalbantoglu, J.; Kamen, Amine
Journal of Virological Methods, 144 (1-2), 2007, p. 32-40

Improvement of Antitumor Activity b Gene Amplification with a Replicating but Nondisseminating Adenovirus

Wed, 03 Jun 2009 10:37:47 +0000

Improvement of Antitumor Activity b Gene Amplification with a Replicating but Nondisseminating Adenovirus
Bourbeau, Denis; Lau, C. J.; Jaime, J.; Koty, Z.; Zehtner, S. P.; Lavoie, G.; Mes-Masson, A-M.; Nalbantoglu, J.; Massie, Bernard
Cancer Research, 2007

Successful compensation for dystrophin deficiency by a helper-dependent adenovirus expressing full-length utrophin

Sun, 01 Mar 2009 03:49:27 +0000

Successful compensation for dystrophin deficiency by a helper-dependent adenovirus expressing full-length utrophin
Deol, Jatinderpal R.; Danialou, Gawiyou; Larochelle, Nancy; Bourget, Mylène; Moon, Joon-Shik; Liu, An-Bang; Gilbert, Rénald; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George
Molecular Therapy, 15 (10), 2007-07-31, p. 1767-1774

Gene Therapy for Duchenne Muscular Dystrophy Using a Gutted Adenovirus Expressing Utrophin

Sun, 01 Mar 2009 03:53:14 +0000

Gene Therapy for Duchenne Muscular Dystrophy Using a Gutted Adenovirus Expressing Utrophin
Deol, Jatinderpal R.; Gilbert, Renald; Danialou, Gawiyou; Bourget, Mylene; Moon, Joon-Shik; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George
13, 2006, p. 354-355

Optimization of regional intraarterial naked DNA-mediated transgene delivery to skeletal muscles in a large animal model

Thu, 10 Sep 2009 10:01:25 +0000

Optimization of regional intraarterial naked DNA-mediated transgene delivery to skeletal muscles in a large animal model
Danialou, Gawiyou; Comtois, Alain; Matecki, Stefan; Nalbantoglu, Josephine; Karpati, George; Gilbert, Rénald; Geoffroy, Pascale; Gilligan, Sandra; Tanguay, Jean-Francois; Petrof, Basil
Molecular Therapy, ISSN: 15250016, 11 (2), 2005-02, p. 257-266

Factors associated with induced chronic inflammation in mdx skeletal muscle cause posttranslational stabilization and augmentation of extrasynaptic sarcolemmal utrophin

Thu, 10 Sep 2009 09:44:21 +0000

Factors associated with induced chronic inflammation in mdx skeletal muscle cause posttranslational stabilization and augmentation of extrasynaptic sarcolemmal utrophin
Waheed, Ishrat; Gilbert, Rénald; Nalbantoglu, Josephine; Guibinga, Ghiabe H.; Petrof, Basil J.; Karpati, George
Human Gene Therapy, 16 (4), 2005-05-04, p. 489-501

Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse muscles

Thu, 10 Sep 2009 10:01:38 +0000

Factors influencing the efficacy, longevity, and safety of electroporation-assisted plasmid-based gene transfer into mouse muscles
Molnar, Maria J.; Gilbert, Rénald; Lu, Yifan; Liu, An-Bang; Guo, Athena; Larochelle, Nancy; Orlopp, Kristian; Lochmuller, Hanns; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George
Molecular Therapy, ISSN: 1525-0016, 10 (3), 2004-07-21, p. 447-455

Sustained Improvement of Muscle Function One Year After Full-Length Dystrophin Gene Transfer into mdx Mice by a Gutted Helper-Dependent Adenoviral Vector

Thu, 10 Sep 2009 09:25:45 +0000

Sustained Improvement of Muscle Function One Year After Full-Length Dystrophin Gene Transfer into mdx Mice by a Gutted Helper-Dependent Adenoviral Vector
Dudley, Roy; Lu, Yifan; Gilbert, Rénald; Matecki, Stefan; Nalbantoglu, Josephine; Petrof, Basil; Karpati, George
Human Gene Therapy, 15 (2), 2004-07-07, p. 145-156

Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status

Sun, 01 Mar 2009 03:57:48 +0000

Suicide gene therapy with an adenovirus expressing the fusion gene CD::UPRT in human glioblastomas: different sensitivities correlate with p53 status
Bourbeau, Denis; Lavoie, Geneviève; Nalbantoglu, Josephine; Massie, Bernard
6 (12), 2004, p. 1320-1332

Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes

Sun, 01 Mar 2009 03:57:17 +0000

Therapeutic gene transfer to dystrophic diaphragm by an adenoviral vector deleted of all viral genes
Matecki, Stefan; Dudley, Roy W. R.; Divangahi, Maziar; Gilbert, Renald; Nalbantoglu, Josephine; Karpati, George; Petrof, Basil J.
American Journal of Physiology: Lung Cellular and Molecular Physiology, ISSN: 1040-0605, 287 (3), 2004-05-21, p. L569-L576

Oligodendrocyte injury in multiple sclerosis: a role for p53

Sun, 01 Mar 2009 03:47:24 +0000

Oligodendrocyte injury in multiple sclerosis: a role for p53
Wosik, Karolina; Antel, Jack; Kuhlmann, Tanja; Bruck, Wolfgang; Massie, Bernard; Nalbantoglu, Josephine
85 (3), 2003, p. 635-644

Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin

Thu, 10 Sep 2009 10:05:22 +0000

Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin
Gilbert, Rénald; Dudley, Roy; Liu, An-Bang; Petrof, Basil; Nalbantoglu, Josephine; Karpati, George
Hum. Mol. Genet., 12 (11), 2003-06-01, p. 1287-1299

Ultrasound increases plasmid-mediated gene transfer to dystrophic muscles without collateral damage

Fri, 11 Sep 2009 01:55:55 +0000

Ultrasound increases plasmid-mediated gene transfer to dystrophic muscles without collateral damage
Danialou, Gawiyou; Comtois, Alain; Dudley, Roy; Nalbantoglu, Josephine; Gilbert, Rénald; Karpati, George; Jones, David H.; Petrof, Basil J.
Molecular Therapy, ISSN: 15250016, 6 (5), 2002-11, p. 687-693

Improved Performance of a Fully Gutted Adenovirus Vector Containing Two Full-Length Dystrophin cDNAs Regulated by a Strong Promoter

Thu, 10 Sep 2009 11:19:43 +0000

Improved Performance of a Fully Gutted Adenovirus Vector Containing Two Full-Length Dystrophin cDNAs Regulated by a Strong Promoter
Gilbert, Rénald; Liu, An-Bang; Petrof, Basil J.; Nalbantoglu, Josephine; Karpati, George
Molecular Therapy, 6 (4), 2002-10, p. 501-209

The short MCK1350 promoter/enhancer allows for sufficient dystrophin expression in skeletal muscles of mdx mice

Sun, 01 Mar 2009 03:49:10 +0000

The short MCK1350 promoter/enhancer allows for sufficient dystrophin expression in skeletal muscles of mdx mice
Larochelle, Nancy; Oualikene, Wahiba; Dunant, Patrick; Massie, Bernard; Karpati, George; Nalbantoglu, Josephine; Lochmuller, Hanns
292 (3), 2002, p. 626-631

Dystrophin expression in muscle following gene transfer with a fully deleted ("Gutted") adenovirus Is markedly improved by trans-acting adenoviral gene products

Thu, 10 Sep 2009 11:47:00 +0000

Dystrophin expression in muscle following gene transfer with a fully deleted ("Gutted") adenovirus Is markedly improved by trans-acting adenoviral gene products
Gilbert, Rénald; Nalbantoglu, Joséphine; Howell, John McC.; Davies, Linda; Fletcher, Susan; Amalfitano, Andrea; Petrof, Basil J.; Kamen, Amine; Massie, Bernard; Karpati, George
Human Gene Therapy, 12 (14), 2001-09-20, p. 1741-1755

Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice

Thu, 10 Sep 2009 09:54:54 +0000

Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice
Ebihara, Satoru; Guibinga, Ghiabe-Henri; Gilbert, Renald; Nalbantoglu, Josephine; Massie, Bernard; Karpati, George; Petrof, Basil J.
Physiological Genomics, ISSN: 1531-2267, 3 (3), 2000-09-08, p. 133-144

Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route

Sun, 01 Mar 2009 03:49:19 +0000

Modulation of Starling forces and muscle fiber maturity permits adenovirus-mediated gene transfer to adult dystrophic (mdx) mice by the intravascular route
Cho, Won-Kyung; Ebihara, Satoru; Nalbantoglu, Josephine; Gilbert, Renald; Massie, Bernard; Holland, Paul; Karpati, George; Petrof, Basil J.
11 (5), 2000, p. 701-714

Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles

Thu, 10 Sep 2009 09:53:38 +0000

Adenovirus-mediated utrophin gene transfer mitigates the dystrophic phenotype of mdx mouse muscles
Gilbert, Rénald; Nalbantoglu, Josephine; Petrof, Basil J.; Ebihara, Satoru; Guibinga, Ghiabe-Henri; Tinsley, Jonathon M.; Kamen, Amine; Massie, Bernard; Davies, Kay E.; Karpati, George
Human Gene Therapy, 10 (8), 1999-05-20, p. 1299-1310

Combinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles

Sun, 01 Mar 2009 04:00:25 +0000

Combinatorial blockade of calcineurin and CD28 signaling facilitates primary and secondary therapeutic gene transfer by adenovirus vectors in dystrophic (mdx) mouse muscles
Guibinga, Ghiabe-Henri; Lochmuller, Hanns; Massie, Bernard; Nalbantoglu, Josephine; Karpati, George; Petrof, Basil J.
72 (6), 1998, p. 4601-4609

High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression

Sun, 01 Mar 2009 03:58:44 +0000

High-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscle of dystrophic dogs: prolongation of expression with immunosuppression
Howell, J. M.; Lochmuller, H.; O'Hara, A.; Fletcher, S.; Kakulas, B. A.; Massie, B.; Nalbantoglu, J.; Karpati, G.
9 (5), 1998, p. 629-634

Adenovirus-mediated dystrophin minigene transfer improves muscle strength in adult dystrophic (MDX) mice

Sun, 01 Mar 2009 03:52:46 +0000

Adenovirus-mediated dystrophin minigene transfer improves muscle strength in adult dystrophic (MDX) mice
Yang, L.; Lochmuller, H.; Luo, J.; Massie, B.; Nalbantoglu, J.; Karpati, G.; Petrof, B. J.
5 (3), 1998, p. 369-379

Study of adenovirus-mediated dystrophin minigene transfer to skeletal muscle by combined microscopic display of adenoviral DNA and dystrophin

Sun, 01 Mar 2009 03:54:41 +0000

Study of adenovirus-mediated dystrophin minigene transfer to skeletal muscle by combined microscopic display of adenoviral DNA and dystrophin
Zhao, Ji-En; Lochmüller, Hanns; Nalbantoglu, Josephine; Allen, Carol; Prescott, Stephen; Massie, Bernard; Karpati, George
Human Gene Therapy, 8 (13), 1997, p. 1565-1573

Gene therapy research for Duchenne and Becker muscular dystrophies

Thu, 10 Sep 2009 02:41:25 +0000

Gene therapy research for Duchenne and Becker muscular dystrophies
Karpati, George; Gilbert, Rénald; Petrof, Basil J.; Nalbantoglu, Josephine
Current Opinion in Neurology, 10, 1997, p. 430-435

The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer

Sun, 01 Mar 2009 03:46:49 +0000

The immunosuppressant FK506 prolongs transgene expression in brain following adenovirus-mediated gene transfer
Durham, H. D.; Alonso-Vanegas, M. A.; Sadikot, A. F.; Zhu, L.; Lochmuller, H.; Massie, B.; Nalbantoglu, J.; Karpati, G.
8 (9-10), 1997, p. 2111-2115

Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice

Sun, 01 Mar 2009 03:49:50 +0000

Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice
Lochmüller, H.; Petrof, B.J.; Pari, G.; Larochelle, N.; Dodelet, V.; Wang, Q.; Allen, C.; Prescott, S.; Massie, B.; Nalbantoglu, J.; Karpati, G.
Gene Therapy, 3 (8), 1996, p. 706-716

Impairment of force generation after adenovirus-mediated gene transfer to muscle is alleviated by adenoviral gene inactivation and host CD8+ T cell deficiency

Sun, 01 Mar 2009 03:49:01 +0000

Impairment of force generation after adenovirus-mediated gene transfer to muscle is alleviated by adenoviral gene inactivation and host CD8+ T cell deficiency
Petrof, B. J.; Lochmuller, H.; Massie, B.; Yang, L.; Macmillan, C.; Zhao, J. E.; Nalbantoglu, J.; Karpati, G.
7 (15), 1996, p. 1813-1826

Adenovirus-Mediated Utrophin Gene Delivery as a Therapy for Duchenne Muscular Dystrophy

Sun, 01 Mar 2009 03:58:28 +0000

Adenovirus-Mediated Utrophin Gene Delivery as a Therapy for Duchenne Muscular Dystrophy
Deol, J. R.; Gilbert, R.; Bourget, M.; Danialou, G.; Moon, J.; Petrof, B. J.; Nalbantoglu, J.; Karpati, G.
(The 58th Annual Meeting of American Academy of Neurology - San Diego, 2006)