TY  - JOUR
ID  - 20548175
AU  - Menard, Robert
AU  - Sulea, Traian
T1  - Selective inhibition of USP7
JO  - Chemistry & Biology
SP  - 437
EP  - 438
VL  - 19
IS  - 4
PY  - 2012
N2  - The deubiquitinating enzyme USP7 is an emerging oncology and antiviral target. Reverdy et al., in this issue of Chemistry & Biology, disclose the first small-molecule inhibitor selective for USP7, which recapitulates its knockdown in cancer cells and hence demonstrates the therapeutic feasibility of USP7 inhibitors.
M1  - 53180
DO  - http://dx.doi.org/10.1016/j.chembiol.2012.04.001
U3  - NRC Biotechnology Research Institute
U3  - Institut de recherche en biotechnologie du CNRC
U3  - National Research Council Canada
U3  - Conseil national de recherches Canada
ER  -