TY  - JOUR
ID  - 21022825
AU  - Isezaki, Jun
AU  - Yoshikawa, Masakazu
AU  - Li, Nanwen
AU  - Robertson, Gilles P.
AU  - Guiver, Michael D.
T1  - Polysulfones with phenylalanine derivatives as chiral selectors – membranes for chiral separation
JO  - Journal of Membrane and Separation Technology
SP  - 1
EP  - 8
VL  - 1
IS  - 1
PY  - 2012
KW  - Chiral separation, membrane, optical resolution, permselectivity, polysulfone
N2  - Polysulfone with a derivative of phenylalanyl residue as a chiral selector (PSf-Ac-D-Phe or PSf-Ac-L-Phe) were prepared by polymer reaction of benzylamine-modified polysulfones with N-a-acetyl-D-phenylalanine or N-a-acetyl-L-phenylalanine. Both polysulfones having a chiral selector gave durable self-standing membranes. The specific rotations of those polymers revealed that the chiral selectors were successfully introduced into the polysulfone. PSf-Ac-D-Phe membrane incorporated L-Glu in preference to D-Glu and vice versa. The chiral separation ability was studied by applying a concentration gradient as a driving force for membrane transport. Permselectivities for those two types of membrane reflected their adsorption selectivities. PSf-Ac-D-Phe membrane selectively transported L-Glu and vice versa. Predicted permselectivities by adopting membrane resistance coincided with the observed ones.
M1  - 53124
DO  - http://dx.doi.org/10.6000/1929-6037.2012.01.01.1
U3  - NRC Institute for Chemical Process and Environmental Technology
U3  - Institut de technologie des procédés chimiques et de l'environnement du CNRC (ITPCE-ICPET)
U3  - National Research Council Canada
U3  - Conseil national de recherches Canada (CNRC-NRC)
ER  -