Amine-decorated nanocrystalline cellulose surfaces: Synthesis, characterization, and surface properties

  1. Get@NRC: Amine-decorated nanocrystalline cellulose surfaces: Synthesis, characterization, and surface properties (Opens in a new window)
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Journal titleCanadian Journal of Chemistry
Pages974981; # of pages: 8
SubjectAminated NCC; Covalent functionalizations; Nanocrystalline cellulose; Nanocrystalline cellulose(NCC); Reactive functional groups; Surface Functionalization; Tempo oxidations; TEMPO-mediated oxidation; Amides; Amination; Carboxylation; Cellulose derivatives; Characterization; Fourier transform infrared spectroscopy; Functional groups; Medical applications; Oxidation; Photoelectrons; Surfaces; Synthesis (chemical); X ray photoelectron spectroscopy; Surface reactions; Amides; Carboxylation; Cellulose; Cellulose Derivatives; Esca; Functional Groups; Oxidation; Photoelectrons; Surfaces; Synthesis; X Ray Spectroscopy
AbstractIn this present work, terminal amino-functionalized nanocrystalline cellulose derivatives were prepared using a simple two-step protecting group-free protocol under aqueous reaction conditions at room temperature. Carboxylate groups were first introduced onto the surface of nanocrystalline cellulose (NCC) via a TEMPO-mediated oxidation. Then, reaction of surface-carboxylated NCC with bifunctional amines of small alkyl chain length by EDC/NHS-mediated coupling furnished the desired aminated NCC via an amide linkage. Surface covalent functionalization was confirmed by Fourier transform infrared spectroscopy, elemental analysis, and X-ray photoelectron spectroscopy. Size, surface charge, morphology, and thermal properties were obtained by various techniques. STEM images revealed no change in structure and morphology of the materials after TEMPO-mediated oxidation but a slight agglomeration was observed after surface covalent functionalization with diamines. While amide linkage confers stability, terminal primary amine groups on the surface of NCC represent a versatile reactive functional group for bioconjugation with other biomolecules for potential biomedical applications. © 2013 Published by NRC Research Press.
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AffiliationNational Research Council Canada (NRC-CNRC); National Institute for Nanotechnology (NINT-INNT)
Peer reviewedYes
NPARC number21269598
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Record identifier3ff24e1a-8954-4ab1-beb2-7795c06d98ff
Record created2013-12-13
Record modified2016-05-09
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