Isolation of steroidal glycosides from the Caribbean sponge Pandaros acanthifolium

Download
  1. Get@NRC: Isolation of steroidal glycosides from the Caribbean sponge Pandaros acanthifolium (Opens in a new window)
DOIResolve DOI: http://doi.org/10.1021/np300520w
AuthorSearch for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for: ; Search for:
TypeArticle
Journal titleJournal of Natural Products
ISSN0163-3864
1520-6025
Volume75
Issue12
Pages20942100
AbstractFour new steroidal glycosides, acanthifoliosides G–J (1–4), were isolated as minor constituents from the Caribbean marine sponge Pandaros acanthifolium. These metabolites are characterized by a highly oxygenated D ring and the presence of a disaccharide rhamnose-glucose residue and a rhamnose at positions C-3 and C-15, respectively. Their structures were established on the basis of extensive interpretation of 1D and 2D NMR data and HRESIMS analyses. The absolute configurations of the glucose and rhamnose sugars were determined by preparing aldose o-tolylthiocarbamate derivatives and comparison to authentic standards by LC/HRESIMS. Acanthifolioside G (1) exhibited antioxidant and cytoprotective activities.
Publication date
LanguageEnglish
AffiliationAquatic and Crop Resource Development; National Research Council Canada
Peer reviewedYes
NPARC number21268909
Export citationExport as RIS
Report a correctionReport a correction
Record identifiera210ab6b-656e-414d-a732-e732b4083cd6
Record created2013-11-25
Record modified2016-05-09
Bookmark and share
  • Share this page with Facebook (Opens in a new window)
  • Share this page with Twitter (Opens in a new window)
  • Share this page with Google+ (Opens in a new window)
  • Share this page with Delicious (Opens in a new window)
Date modified: