Identification of labile UDP-ketosugars in helicobacter pylori, campylobacter jejuni and pseudomonas aeruginosa: key metabolites used to make glycan virulence factors

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DOIResolve DOI: http://doi.org/10.1002/cbic.200600298
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TypeArticle
Journal titleChemMedChem
ISSN1860-7179
1860-7187
Volume7
Issue12
Pages18651868
AbstractUDP-hexos-4-ulose sugars occupy a central role in the biosynthesis of lipopolysaccharides, capsular polysaccharides, and antibiotics in bacteria. Little is known about these sugars as they are labile compounds that are produced in minute quantities within the bacterial cell. Examination of the PglF, PseB, WbjB, and WbjC reactions directly with NMR lead to the first detailed structural description of UDP-hexos-4-ulose sugars in various bacteria.
Publication date
PublisherWiley
LanguageEnglish
AffiliationNational Research Council Canada; NRC Institute for Biological Sciences
Peer reviewedYes
NPARC number23002072
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Record identifieraf03c488-cbee-4013-b530-60724fec2e41
Record created2017-08-04
Record modified2017-08-04
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