Infrared spectroscopic characterization of human white matter, grey matter and multiple sclerosis lesions

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TypeBook Chapter
Proceedings title9th International Conference on Fourier Transform Spectroscopy
Series titleProceedings of SPIE; no. 2089
Conference9th International Conference on Fourier Transform Spectroscopy, August 23, 1993, Calgary, Alberta, Canada
Pages494495; # of pages: 2
AbstractFT-IR spectroscopy has been used to characterize white matter, grey matter, and multiple sclerosis (MS) plaques from human central nervous system (CNS) tissue. Discrimination among these three tissue types is possible due to variations in composition. Spectra of white matter exhibit strong lipid absorptions. In contrast, spectra of grey matter reveal a reduced lipid contribution and a significant absorption from water. MS plaques exhibit spectra indicative of lipid loss and, depending upon whether the plaques are chronic or acute, changes in the protein and/or water content.
Publication date
AffiliationNational Research Council Canada; NRC Institute for Biodiagnostics
Peer reviewedYes
NRC number773
NPARC number9742229
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Record identifierc496fb9c-1f5a-419f-badd-b5cb3bb6ee29
Record created2009-07-17
Record modified2017-09-13
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